Roy Hodgson and Carlo Ancelotti put their respective winning records on the line as Crystal Palace and Everton meet at Selhurst Park in one of four Premier League games taking place on Saturday.
Elsewhere, Brighton can make it two wins in a row and condemn Manchester United to a second straight league defeat with victory at the Amex Stadium in the lunchtime kick-off.
Chelsea will be looking bounce back from defeat to Liverpool last Sunday while Ralph Hasenhuttl takes his Southampton side to Burnley in search of the Saints’ first win of the campaign.
Brighton vs Man Utd, 12:30
Brighton had the better of things against Chelsea in their opening game only for poor defending and clinical finishing resulting in them beaten 3-1, but Graham Potter’s side has bounced back well, with three straight clean sheet wins, with two of those coming in the Carabao Cup.
As for Manchester United, they followed-up a disastrous 3-1 home defeat in their Premier League opener with a victory at Luton in the EFLCup and will be keen to kick-start their league campaign at what has been a close contest in recent seasons.
The Seagulls have won three of their last four home games against Man Utd, although the Red Devils have won the sides’ last three meetings, including a 3-0 win in this fixture last season.
Crystal Palace v Everton, 15:00
Nobody would have predicted this being an early-season title decider at the start of the campaign and it probably won’t prove to be in the end, though one could well be losing their 100% record come 5pm on Saturday.
Palace have won their two opening fixtures of a Premier League campaign for the first time with victories over Southampton and then at Old Trafford last Saturday with Wilfried Zaha – a long-time transfer target for the Blues – bagging three goals in two games this season having managed four goals in 38 last campaign.
The Blues, who are also two from two, have six clean sheets in their last seven visits to Selhurst Park while Palace are winless in 11 games against the Toffees dating back to a 3-2 victory at Goodison Park the last time Everton were in top-four contention.
West Brom v Chelsea, 17:30
Frank Lampard will be desperate to bounce back with a win after his side were beaten at home by Liverpool last weekend, but Chelsea are far from firing on all cylinders at the moment.
They may have battered Barnsley in the EFL Cup on Wednesday but the Blues can lay claim to one clean sheet from their 20 Premier League away games under Frank Lampard and that must improve if they are to get anything at the Hawthornes.
However, Chelsea have inflicted more Premier League defeats on the Baggies (18) than any other side and combine that with the fact that Albion have conceded eight goals so far – the most they’ve ever shipped in the first two games of a league campaign – and it’s hard to find many positives for Slaven Bilic’s side.
Burnley v Southampton, 20:00
Burnley have a good record against Southampton with the Clarets’ five home games without defeat to Saints their longest such run against any opponent and Sean Dyche will be keen to inflict more misery on a side who are winless from their opening two games of the season.
Ralph Hassenhuttl’s side went down 5-2 at home to Spurs last week, despite taking the lead in the first half and looking the better team for much of the first 45 minutes.
That’s somewhat typical of Southampton though as no Premier League side has dropped more points from winning positions than Southampton (37), not the kind of record you want going away to a side who are more than capable of causing problems for their opponents.
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