Champions Manchester City face a trip to Tottenham, Manchester United play Leeds at Old Trafford, while Champions League winners Chelsea host Crystal Palace on the opening weekend of the 2021/22 Premier League season.
Pep Guardiola’s Manchester City are favourites to retain their Premier League title but face a testing opening run of games, with Spurs, Norwich, Arsenal, Leicester, Southampton, Chelsea and Liverpool their opening seven opponents.
But the Blues will be given extra confidence by the fact that they have won their first league match of the season in each of their past 10 campaigns, the joint-longest such run in top-flight history alongside Aston Villa between 1891-92 and 1900-01.
In the other stand-out games, Norwich and Watford, who came up last season, face Liverpool and Aston Villa respectively and newly promoted Brentford will host Arsenal in their first top-flight game since the 1946-47 season.
Liverpool are unbeaten in their past 14 Premier League matches against Norwich, and the Canaries are winless in their first Premier League match of the season in each of their past eight attempts – a run dating back to 1992-93.
Everton, who have not lost their opening match in any of the past nine Premier League campaigns, welcome Southampton to Goodison Park on the opening weekend, who have won their opening fixture in just one of their past 14 Premier League campaigns.
The first fixtures will take place on 14 August and, though it’s not yet known how many fans will be able to attend the opening fixtures of the new season, the Premier League has said it is: “committed to the ambition of having full stadiums, including away supporters” from the start of the season.
The first north London derby between Spurs and Arsenal is due to take place on 25 September, while the first Merseyside derby of the season will see Everton host Liverpool at Goodison Park in a midweek fixture on 30 November.
The first Manchester derby sees United take on City at Old Trafford on 11 November, while eye-catching Boxing Day fixtures include Liverpool v Leeds and Manchester City against Leicester.
The penultimate round of Premier League fixtures will take place on Sunday 15 May in order to accommodate the FA Cup final a day earlier, with the final day of the season scheduled for 22 May.
First round of fixtures in full
Brentford v Arsenal
Burnley v Brighton
Chelsea v Crystal Palace
Everton v Southampton
Leicester City v Wolverhampton
Manchester United v Leeds United
Newcastle United v West Ham United
Norwich City v Liverpool
Tottenham Hotspur v Manchester City
Watford v Aston Villa
The Boxing Day games
Aston Villa vs Chelsea
Brighton vs Brentford
Burnley vs Everton
Liverpool vs Leeds United
Manchester City vs Leicester City
Newcastle United vs Manchester United
Norwich City vs Arsenal
Tottenham Hotspur vs Crystal Palace
West Ham United vs Southampton
Wolverhampton vs Watford
The Final day games
Arsenal vs Everton
Brentford vs Leeds United
Brighton vs West Ham United
Burnley vs Newcastle United
Chelsea vs Watford
Crystal Palace vs Manchester United
Leicester City vs Southampton
Liverpool vs Wolverhampton
Manchester City vs Aston Villa
Norwich City vs Tottenham Hotspur
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